Title : The domain organization of p67 phox, a protein required for activation of the superoxide-producing NADPH oxidase in phagocytes.

Pub. Date : 2009

PMID : 20375610






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 In activation of the oxidase, the multidomain protein p67(phox)plays a central role: it translocates to the membrane as a ternary complex with p47(phox)and p40(phox), and interacts with the small GTPase Rac to assemble with the membrane-integrated catalytic protein gp91(phox), leading to superoxide production. Superoxides pleckstrin Homo sapiens