Title : alpha(1)- and alpha(2)-Adrenoceptor hyporesponsiveness in isolated bisected vas deferens of bile duct-ligated rats.

Pub. Date : 2010 Jul

PMID : 20345427






2 Functional Relationships(s)
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1 Our results indicate that in vas deferens of BDL animals, the concentration-response curve of both phenylephrine and clonidine shifted to rightward compared to control group, while the position of concentration-response curve of sham group did not change significantly (P > 0.05). Phenylephrine arginine vasopressin Rattus norvegicus
2 Our conclusion is that the cholestasis induces hyporesponsiveness to phenylephrine and clonidine in epididymal (alpha(1)-adrenoceptors) and prostatic (alpha(2)-adrenoceptors) halves of rat vas deferens respectively. Phenylephrine arginine vasopressin Rattus norvegicus