Title : Inhibition of oligopeptide transporter suppress growth of human pancreatic cancer cells.

Pub. Date : 2010 Jun 14

PMID : 20307658






2 Functional Relationships(s)
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1 We here synthesized two novel dipeptides, l-phenylalanyl sarcosine (Phe-Sar) and 4-(4-methoxyphenyl)-l-phenylalanyl sarcosine (Bip(OMe)-Sar), and examined their effect on the growth of human pancreatic cancer AsPC-1 cells, which are known to highly express oligopeptide transporter PEPT1/SLC15A1. Dipeptides solute carrier family 15 member 1 Homo sapiens
2 We here synthesized two novel dipeptides, l-phenylalanyl sarcosine (Phe-Sar) and 4-(4-methoxyphenyl)-l-phenylalanyl sarcosine (Bip(OMe)-Sar), and examined their effect on the growth of human pancreatic cancer AsPC-1 cells, which are known to highly express oligopeptide transporter PEPT1/SLC15A1. Dipeptides solute carrier family 15 member 1 Homo sapiens