Pub. Date : 2010 Mar 2
PMID : 20099873
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Human DNA glycosylase NEIL1 exhibits a superior ability to remove oxidized guanine lesions guanidinohydantoin (Gh) and spiroiminodihydantoin (Sp) from duplex DNA in comparison to other substrates. | spiroiminodihydantoin | nei like DNA glycosylase 1 | Homo sapiens |
| 2 | Human DNA glycosylase NEIL1 exhibits a superior ability to remove oxidized guanine lesions guanidinohydantoin (Gh) and spiroiminodihydantoin (Sp) from duplex DNA in comparison to other substrates. | spiroiminodihydantoin | nei like DNA glycosylase 1 | Homo sapiens |
| 3 | In this work, Gh and Sp lesions in bubble, bulge, and single-stranded DNA were found to be good substrates for NEIL1 but were typically excised at much slower rates than from canonical duplex substrates. | spiroiminodihydantoin | nei like DNA glycosylase 1 | Homo sapiens |