Title : The N-terminal domain of human holocarboxylase synthetase facilitates biotinylation via direct interaction with the substrate protein.

Pub. Date : 2010 Feb 19

PMID : 20085763






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The domain interacts not only with biotin acceptor protein, but also with the catalytic domain of hHCS, as shown by nuclear magnetic resonance (NMR) experiments. Biotin holocarboxylase synthetase Homo sapiens
2 We propose that the N-terminal domain of hHCS recognizes the charged region of biotin acceptor protein, distinctly from the recognition by the catalytic domain. Biotin holocarboxylase synthetase Homo sapiens