Title : CYP7B1-mediated metabolism of 5alpha-androstane-3alpha,17beta-diol (3alpha-Adiol): a novel pathway for potential regulation of the cellular levels of androgens and neurosteroids.

Pub. Date : 2009 Dec

PMID : 19732851






1 Functional Relationships(s)
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1 3alpha-Adiol was found to undergo NADPH-dependent metabolism into 6- and 7-hydroxymetabolites in incubations with porcine microsomes and human kidney-derived HEK293 cells, which are high in CYP7B1 content. 6- and 7-hydroxymetabolites cytochrome P450 family 7 subfamily B member 1 Homo sapiens