Title : Involvement of peroxisome proliferator-activated receptor gamma in gonadal steroidogenesis and steroidogenic acute regulatory protein expression.

Pub. Date : 2009

PMID : 19698295






2 Functional Relationships(s)
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1 In the present study, we used ciglitazone to selectively activate PPARgamma and examine its role in STAR-mediated steroidogenesis in immortalised KK1 mouse granulosa cells and MA-10 mouse Leydig tumour cells. ciglitazone peroxisome proliferator activated receptor gamma Mus musculus
2 Ciglitazone-activated PPARgamma appears to increase the sensitivity of Leydig and granulosa cells to cAMP stimulation, possibly via upregulation of c-JUN expression. ciglitazone peroxisome proliferator activated receptor gamma Mus musculus