Pub. Date : 2009 Oct 16
PMID : 19690166
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Furthermore, the ERRgamma inverse agonist GSK5182 enhances the interaction of SMILE with ERRgamma and SMILE-mediated repression. | GSK5182 | estrogen related receptor gamma | Homo sapiens |
| 2 | Furthermore, the ERRgamma inverse agonist GSK5182 enhances the interaction of SMILE with ERRgamma and SMILE-mediated repression. | GSK5182 | estrogen related receptor gamma | Homo sapiens |
| 3 | Moreover, chromatin immunoprecipitation assays revealed that GSK5182 augments the association of SMILE and SIRT1 on the promoter of the ERRgamma target PDK4. | GSK5182 | estrogen related receptor gamma | Homo sapiens |
| 4 | GSK5182 and adenoviral overexpression of SMILE cooperate to repress ERRgamma-induced PDK4 gene expression, and this repression is released by overexpression of a catalytically defective SIRT1 mutant. | GSK5182 | estrogen related receptor gamma | Homo sapiens |