Title : Lipoprotein-associated phospholipase A(2) and atherosclerosis.

Pub. Date : 2009 Oct

PMID : 19667981






2 Functional Relationships(s)
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1 RECENT FINDINGS: Lp-PLA2, also known as platelet-activating factor acetylhydrolase, rapidly cleaves oxidized phosphatidylcholine molecules produced during the oxidation of LDL and atherogenic lipoprotein Lp(a), generating the soluble proinflammatory and proapoptotic lipid mediators, lyso-phosphatidylcholine and oxidized nonesterified fatty acids. Fatty Acids, Nonesterified phospholipase A2 group VII Homo sapiens
2 RECENT FINDINGS: Lp-PLA2, also known as platelet-activating factor acetylhydrolase, rapidly cleaves oxidized phosphatidylcholine molecules produced during the oxidation of LDL and atherogenic lipoprotein Lp(a), generating the soluble proinflammatory and proapoptotic lipid mediators, lyso-phosphatidylcholine and oxidized nonesterified fatty acids. Fatty Acids, Nonesterified phospholipase A2 group VII Homo sapiens