Title : Genistein and beta-carotene enhance the growth-inhibitory effect of trichostatin A in A549 cells.

Pub. Date : 2010 Feb

PMID : 19639378






3 Functional Relationships(s)
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1 Genistein significantly enhanced TSA-induced caspase-3 activity in A549 cells by 34% at 24 h, and the caspase-3 inhibitor partly inhibited the enhancing effect of genistein on TSA-induced apoptosis. Genistein caspase 3 Homo sapiens
2 Genistein significantly enhanced TSA-induced caspase-3 activity in A549 cells by 34% at 24 h, and the caspase-3 inhibitor partly inhibited the enhancing effect of genistein on TSA-induced apoptosis. Genistein caspase 3 Homo sapiens
3 Genistein exerts its effect, at least partly, by increasing caspase-3 activity; whereas beta-carotene may enhance TSA-induced cell death mainly through a caspase-3-independent pathway. Genistein caspase 3 Homo sapiens