Title : Nicotine-reduced endothelial progenitor cell senescence through augmentation of telomerase activity via the PI3K/Akt pathway.

Pub. Date : 2009

PMID : 19499400






3 Functional Relationships(s)
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1 Nicotine-reduced endothelial progenitor cell senescence through augmentation of telomerase activity via the PI3K/Akt pathway. Nicotine AKT serine/threonine kinase 1 Homo sapiens
2 Nicotine significantly increased telomerase activity and phosphorylation of Akt, a downstream effector of phosphoinositide 3-kinase (PI3K). Nicotine AKT serine/threonine kinase 1 Homo sapiens
3 CONCLUSIONS: The results of the present study indicate that nicotine delays the onset of EPC senescence, which might be related to activation of telomerase through the PI3K/Akt pathway. Nicotine AKT serine/threonine kinase 1 Homo sapiens