Title : EWS/ETS regulates the expression of the Dickkopf family in Ewing family tumor cells.

Pub. Date : 2009

PMID : 19247449






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 We showed that EFT-specific EWS/ETS fusion proteins enhance the DKK2 promoter activity, but not DKK1 promoter activity, via ets binding sites (EBSs) in the 5" upstream region. ebss EWS RNA binding protein 1 Homo sapiens
2 EWS/ETS-mediated transactivation of the promoter was suppressed by the deletion and mutation of EBSs located upstream of the DKK2 gene. ebss EWS RNA binding protein 1 Homo sapiens