Title : Phospho-p70S6K/p85S6K and cdc2/cdk1 are novel targets for diffuse large B-cell lymphoma combination therapy.

Pub. Date : 2009 Mar 1

PMID : 19223503






1 Functional Relationships(s)
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1 The combination of rapamycin and UCN-01 synergistically inhibited the DLBCL cell proliferation by inducing G1 arrest as well as apoptosis by suppressing the phosphorylation of p70S6K/p85S6K and CDC2 expression. 7-hydroxystaurosporine cyclin dependent kinase 1 Homo sapiens