Title : A Pyk2-Vav1 complex is recruited to beta3-adhesion sites to initiate Rho activation.

Pub. Date : 2009 Apr 28

PMID : 19207108






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 These results indicate that Pyk2 is a critical signalling molecule downstream of beta3 integrin tyrosine phosphorylation and mediates Vav1 recruitment to accomplish actin reorganization necessary for adhesion. Tyrosine protein tyrosine kinase 2 beta Homo sapiens