Title : ACC2 is expressed at high levels in human white adipose and has an isoform with a novel N-terminus [corrected].

Pub. Date : 2009

PMID : 19190759






3 Functional Relationships(s)
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Protein Name
Organism
1 Acetyl-CoA carboxylases ACC1 and ACC2 catalyze the carboxylation of acetyl-CoA to malonyl-CoA, regulating fatty-acid synthesis and oxidation, and are potential targets for treatment of metabolic syndrome. Fatty Acids acetyl-CoA carboxylase beta Homo sapiens
2 Expression of ACC1 in rodent lipogenic tissues and ACC2 in rodent oxidative tissues, coupled with the predicted localization of ACC2 to the mitochondrial membrane, have suggested separate functional roles for ACC1 in lipogenesis and ACC2 in fatty acid oxidation. Fatty Acids acetyl-CoA carboxylase beta Homo sapiens
3 Expression of ACC1 in rodent lipogenic tissues and ACC2 in rodent oxidative tissues, coupled with the predicted localization of ACC2 to the mitochondrial membrane, have suggested separate functional roles for ACC1 in lipogenesis and ACC2 in fatty acid oxidation. Fatty Acids acetyl-CoA carboxylase beta Homo sapiens