Pub. Date : 2009 Jan
PMID : 19145512
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Stat3 activation was dose-dependently suppressed by EGCG in tumor cells, and an average of 53.5% reduction was observed in tumor tissues, but EGCG treatment did not change total Stat3 expression. | epigallocatechin gallate | signal transducer and activator of transcription 3 | Mus musculus |
2 | Stat3 activation was dose-dependently suppressed by EGCG in tumor cells, and an average of 53.5% reduction was observed in tumor tissues, but EGCG treatment did not change total Stat3 expression. | epigallocatechin gallate | signal transducer and activator of transcription 3 | Mus musculus |
3 | CONCLUSION: EGCG reduces expression of VEGF in gastric cancer by inhibiting activation of Stat3, thereby inhibits tumor growth and angiogenesis of gastric cancer. | epigallocatechin gallate | signal transducer and activator of transcription 3 | Mus musculus |