Title : Mechanisms of pH-gradient driven transport mediated by organic anion polypeptide transporters.

Pub. Date : 2009 Mar

PMID : 19129463






4 Functional Relationships(s)
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1 Using online intracellular pH measurements in OATP/Oatp-transfected Chinese Hamster Ovary (CHO)-K1 cells, we could demonstrate the presence of a 4,4"-diisothiocyanatostilbene-2,2"-disulfonic acid-sensitive chloride/bicarbonate exchanger in CHO-K1 cells and that OATP/Oatp-mediated substrate transport is paralleled by bicarbonate efflux. cho solute carrier organic anion transporter family member 1A2 Homo sapiens
2 Using online intracellular pH measurements in OATP/Oatp-transfected Chinese Hamster Ovary (CHO)-K1 cells, we could demonstrate the presence of a 4,4"-diisothiocyanatostilbene-2,2"-disulfonic acid-sensitive chloride/bicarbonate exchanger in CHO-K1 cells and that OATP/Oatp-mediated substrate transport is paralleled by bicarbonate efflux. cho solute carrier organic anion transporter family member 1A2 Homo sapiens
3 Using online intracellular pH measurements in OATP/Oatp-transfected Chinese Hamster Ovary (CHO)-K1 cells, we could demonstrate the presence of a 4,4"-diisothiocyanatostilbene-2,2"-disulfonic acid-sensitive chloride/bicarbonate exchanger in CHO-K1 cells and that OATP/Oatp-mediated substrate transport is paralleled by bicarbonate efflux. cho solute carrier organic anion transporter family member 1A2 Homo sapiens
4 Using online intracellular pH measurements in OATP/Oatp-transfected Chinese Hamster Ovary (CHO)-K1 cells, we could demonstrate the presence of a 4,4"-diisothiocyanatostilbene-2,2"-disulfonic acid-sensitive chloride/bicarbonate exchanger in CHO-K1 cells and that OATP/Oatp-mediated substrate transport is paralleled by bicarbonate efflux. cho solute carrier organic anion transporter family member 1A2 Homo sapiens