Title : Adrenocortical response to low-dose ACTH test in female patients with rheumatoid arthritis.

Pub. Date : 2008 Dec

PMID : 19120158






2 Functional Relationships(s)
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1 ACTH-induced maximal rise in plasma DHEA was significantly lower in RA patients when compared to controls (Delta(max): 2.59 +/- 0.68 in RA versus 5.57 +/- 1.25 ng/mL in C, P= 0.015). Dehydroepiandrosterone proopiomelanocortin Homo sapiens
2 The present results show decreased secretion of cortisol and DHEA in RA patients in response to ACTH, suggesting a subtle HPA hypofunction at the adrenocortical level. Dehydroepiandrosterone proopiomelanocortin Homo sapiens