Title : Nox2-containing NADPH oxidase and xanthine oxidase are sources of superoxide in mouse trachea.

Pub. Date : 2009 Mar

PMID : 19076165






5 Functional Relationships(s)
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1 Nox2-containing NADPH oxidase and xanthine oxidase are sources of superoxide in mouse trachea. Superoxides xanthine dehydrogenase Mus musculus
2 The aim of the present study was to elucidate whether the two key candidate superoxide-producing enzymes in mammalian cells, namely Nox2-containing NADPH oxidase and xanthine oxidase, are responsible for superoxide production in mouse trachea. Superoxides xanthine dehydrogenase Mus musculus
3 The aim of the present study was to elucidate whether the two key candidate superoxide-producing enzymes in mammalian cells, namely Nox2-containing NADPH oxidase and xanthine oxidase, are responsible for superoxide production in mouse trachea. Superoxides xanthine dehydrogenase Mus musculus
4 Superoxide production by isolated trachea, as measured by L-012-dependent chemiluminescence, was markedly reduced by superoxide dismutase (300 U/mL) and the xanthine oxidase inhibitor allopurinol (100 micromol/L). Superoxides xanthine dehydrogenase Mus musculus
5 These novel findings suggest that superoxide production by mouse trachea is attributed to both Nox2-containing NADPH oxidase and xanthine oxidase. Superoxides xanthine dehydrogenase Mus musculus