Title : Integrin-associated Lyn kinase promotes cell survival by suppressing acid sphingomyelinase activity.

Pub. Date : 2008 Oct 24

PMID : 18682390

1 Functional Relationships(s)
Compound Name
Protein Name
1 In OLs, knockdown of Lyn with small interfering RNA resulted in OL apoptosis with concomitant accumulation of C(16)-ceramide due to activation of acid sphingomyelinase (ASMase) and sphingomyelin hydrolysis. N-palmitoylsphingosine LYN proto-oncogene, Src family tyrosine kinase Mus musculus