Pub. Date : 2008 Jul 1
PMID : 18593940
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Functional genomics identifies ABCC3 as a mediator of taxane resistance in HER2-amplified breast cancer. | taxane | ATP binding cassette subfamily C member 3 | Homo sapiens |
| 2 | We also show that amplification of ABCC3 is present in primary breast tumors and that it occurs predominantly in HER2-amplified and luminal tumors, and we report on development of a specific fluorescence in situ hybridization assay that may have utility as a predictive biomarker of taxane resistance in breast cancer. | taxane | ATP binding cassette subfamily C member 3 | Homo sapiens |