Title : The coffee diterpene kahweol induces heme oxygenase-1 via the PI3K and p38/Nrf2 pathway to protect human dopaminergic neurons from 6-hydroxydopamine-derived oxidative stress.

Pub. Date : 2008 Jul 23

PMID : 18593583






1 Functional Relationships(s)
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1 Pretreatment of SH-SY5Y cells with kahweol significantly reduced 6-OHDA-induced generation of ROS, caspase-3 activation, and subsequent cell death. Oxidopamine caspase 3 Homo sapiens