Title : Synthesis of novel C17 steroidal carbamates. Studies on CYP17 action, androgen receptor binding and function, and prostate cancer cell growth.

Pub. Date : 2008 Nov

PMID : 18582482






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The carbamate moiety at C17 allowed tight binding of the synthesized compounds to both wild-type (wt-) and mutated AR. Carbamates androgen receptor Homo sapiens