Title : Arsenic trioxide decreases AKT protein in a caspase-dependent manner.

Pub. Date : 2008 Jun

PMID : 18566239






1 Functional Relationships(s)
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1 We show that As2O3 decreases AKT protein via caspase-mediated degradation, abrogated by caspase-6, caspase-8, caspase-9, and caspase-3 inhibitors but not proteosome inhibitors. Arsenic Trioxide caspase 3 Homo sapiens