Title : Metallothionein-III protects against 6-hydroxydopamine-induced oxidative stress by increasing expression of heme oxygenase-1 in a PI3K and ERK/Nrf2-dependent manner.

Pub. Date : 2008 Sep 15

PMID : 18554677






1 Functional Relationships(s)
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1 Pretreatment of SH-SY5Y cells with MT-III significantly reduced 6-OHDA-induced generation of ROS, caspase-3 activation, and subsequent cell death. Oxidopamine caspase 3 Homo sapiens