Title : Superior removal of hydantoin lesions relative to other oxidized bases by the human DNA glycosylase hNEIL1.

Pub. Date : 2008 Jul 8

PMID : 18543945






1 Functional Relationships(s)
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1 Most notably, quantitative examination of the substrate specificity with hNEIL1 revealed that the hydantoin lesions are excised much more efficiently (>100-fold faster) than the reported standard substrates thymine glycol (Tg) and 5-hydroxycytosine (5-OHC). 5-ohc nei like DNA glycosylase 1 Homo sapiens