Pub. Date : 2008 Jun 11
PMID : 18498770
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Tyrosine phosphorylation of HPK1 by activated Src promotes ischemic brain injury in rat hippocampal CA1 region. | Tyrosine | SRC proto-oncogene, non-receptor tyrosine kinase | Rattus norvegicus |
| 2 | We speculate that this unique signaling pathway through the tyrosine phosphorylation of HPK1 promotes ischemic brain injury by activated Src via N-methyl-d-aspartate receptor and, ultimately, the activation of the MLK3-MKK7-JNK3 pathway after cerebral ischemia. | Tyrosine | SRC proto-oncogene, non-receptor tyrosine kinase | Rattus norvegicus |