Pub. Date : 2008 Aug
PMID : 18448488
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Rapid activation of Stat3 and ERK1/2 by nicotine modulates cell proliferation in human bladder cancer cells. | Nicotine | signal transducer and activator of transcription 3 | Homo sapiens |
| 2 | We found that nicotine simultaneously activates Stat3 and extracellular signal regulated kinase 1/2 (ERK1/2) in T24 cells. | Nicotine | signal transducer and activator of transcription 3 | Homo sapiens |
| 3 | We conclude that through nAChR and beta-adrenoceptors, nicotine activates ERK1/2 and Stat3 signaling pathways, leading to Cyclin D1 expression and cell proliferation. | Nicotine | signal transducer and activator of transcription 3 | Homo sapiens |