Title : Opposite effects of spermine and arcaine on responses of N-methyl-D-aspartate receptors expressed in Xenopus oocytes.

Pub. Date : 1991 Nov 11

PMID : 1838407






3 Functional Relationships(s)
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1 The ability of polyamines to modulate N-methyl-D-aspartate (NMDA) receptor function was investigated in Xenopus oocytes injected with rat brain mRNA. Polyamines glutamate ionotropic receptor NMDA type subunit 1 L homeolog Xenopus laevis
2 These findings demonstrate that polyamines exert both positive and negative modulatory control of the NMDA receptor expressed in Xenopus oocytes, and suggest that spermine and arcaine act at distinct sites in the NMDA receptor complex. Polyamines glutamate ionotropic receptor NMDA type subunit 1 L homeolog Xenopus laevis
3 These findings demonstrate that polyamines exert both positive and negative modulatory control of the NMDA receptor expressed in Xenopus oocytes, and suggest that spermine and arcaine act at distinct sites in the NMDA receptor complex. Polyamines glutamate ionotropic receptor NMDA type subunit 1 L homeolog Xenopus laevis