Title : The function of interleukin 17 in the pathogenesis of rheumatoid arthritis.

Pub. Date : 2007 Sep-Oct

PMID : 18219763

1 Functional Relationships(s)
Compound Name
Protein Name
1 IL-17 binding to an IL-17 receptor expressed on epithelial, endothelial, and fibroblastic stromal cells triggers the activation of transcription factor NF-kappaB and mitogen-activated protein kinase (p-38), which in turn results in the secretion of IL-1, TNF-alpha, IL-6, IL-8, or prostaglandin E2. Dinoprostone C-X-C motif chemokine ligand 8 Homo sapiens