Title : Antithrombin activity is inhibited by acrolein and homocysteine thiolactone: Protection by cysteine.

Pub. Date : 2008 Feb 13

PMID : 18206177






1 Functional Relationships(s)
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1 Antithrombin is one of the most important inhibitors of blood coagulation Since its activation by heparin binding requires critical interactions involving 3 Lys residues; we hypothesized that acrolein or homocysteine thiolactone impair antithrombin activity. Lysine serpin family C member 1 Homo sapiens