Title : Identification of oxysterol 7alpha-hydroxylase (Cyp7b1) as a novel retinoid-related orphan receptor alpha (RORalpha) (NR1F1) target gene and a functional cross-talk between RORalpha and liver X receptor (NR1H3).

Pub. Date : 2008 Mar

PMID : 18055760






2 Functional Relationships(s)
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1 In this study, we revealed a novel function of RORalpha (NR1F1) in regulating the oxysterol 7alpha-hydroxylase (Cyp7b1), an enzyme critical for the homeostasis of cholesterol, bile acids, and oxysterols. Oxysterols cytochrome P450, family 7, subfamily b, polypeptide 1 Mus musculus
2 In this study, we revealed a novel function of RORalpha (NR1F1) in regulating the oxysterol 7alpha-hydroxylase (Cyp7b1), an enzyme critical for the homeostasis of cholesterol, bile acids, and oxysterols. Oxysterols cytochrome P450, family 7, subfamily b, polypeptide 1 Mus musculus