Title : Insulin-like growth factor-1 potentiates platelet activation via the IRS/PI3Kalpha pathway.

Pub. Date : 2007 Dec 15

PMID : 17827393






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Furthermore, IGF-1 stimulates tyrosine phosphorylation of insulin receptor substrate-1 (IRS-1) and IRS-2 and their association with the p85 subunit of phosphoinositide-3 kinase (PI3K). Tyrosine insulin like growth factor 1 Homo sapiens
2 IGF-1-stimulated tyrosine phosphorylation of IRS-1 and IRS-2 and subsequent p85 binding is transient and precedes phosphorylation of protein kinase B (PKB) on Ser473. Tyrosine insulin like growth factor 1 Homo sapiens