Pub. Date : 2007 Dec 15
PMID : 17827393
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Furthermore, IGF-1 stimulates tyrosine phosphorylation of insulin receptor substrate-1 (IRS-1) and IRS-2 and their association with the p85 subunit of phosphoinositide-3 kinase (PI3K). | Tyrosine | insulin like growth factor 1 | Homo sapiens |
2 | IGF-1-stimulated tyrosine phosphorylation of IRS-1 and IRS-2 and subsequent p85 binding is transient and precedes phosphorylation of protein kinase B (PKB) on Ser473. | Tyrosine | insulin like growth factor 1 | Homo sapiens |