Title : Role of the small GTPase Rac in p22phox-dependent NADPH oxidases.

Pub. Date : 2007 Sep

PMID : 17583407






2 Functional Relationships(s)
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1 When these oxidases use Noxo1 as an organizer instead of p47(phox), they produce a small but significant amount of superoxide without expression of Rac1(Q61L), although the production is enhanced by Rac1(Q61L). Superoxides Rac family small GTPase 1 Homo sapiens
2 We also demonstrate that, in the Nox3-based oxidase containing solely p67(phox) as supportive protein, expression of Rac1(Q61L) enhances not only superoxide production but also membrane translocation of p67(phox). Superoxides Rac family small GTPase 1 Homo sapiens