Title : Tissue-specific and reversible RNA interference in transgenic mice.

Pub. Date : 2007 Jul

PMID : 17572676






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Transgenic mice harboring a tet-responsive RNA polymerase II promoter driving a microRNA-based short hairpin RNA targeting the tumor suppressor Trp53 reversibly express short hairpin RNA when crossed with existing mouse strains expressing general or tissue-specific "tet-on" or "tet-off" transactivators. Tetracycline transformation related protein 53 Mus musculus
2 Transgenic mice harboring a tet-responsive RNA polymerase II promoter driving a microRNA-based short hairpin RNA targeting the tumor suppressor Trp53 reversibly express short hairpin RNA when crossed with existing mouse strains expressing general or tissue-specific "tet-on" or "tet-off" transactivators. Tetracycline transformation related protein 53 Mus musculus
3 Transgenic mice harboring a tet-responsive RNA polymerase II promoter driving a microRNA-based short hairpin RNA targeting the tumor suppressor Trp53 reversibly express short hairpin RNA when crossed with existing mouse strains expressing general or tissue-specific "tet-on" or "tet-off" transactivators. Tetracycline transformation related protein 53 Mus musculus