Title : Contribution of the conserved amino acids of the melanocortin-4 receptor in [corrected] [Nle4,D-Phe7]-alpha-melanocyte-stimulating [corrected] hormone binding and signaling.

Pub. Date : 2007 Jul 27

PMID : 17545153






1 Functional Relationships(s)
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1 Further mutagenesis studies indicate that conserved residues Glu(100) in TM2, Asp(122), Asp(126) in TM3 and Trp(258), Phe(261), His(264) in TM6 are involved in alpha-MSH binding and signaling. Glutamic Acid proopiomelanocortin Homo sapiens