Title : Expression of sialidase Neu2 in leukemic K562 cells induces apoptosis by impairing Bcr-Abl/Src kinases signaling.

Pub. Date : 2007 May 11

PMID : 17374613






1 Functional Relationships(s)
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1 In fact, three cytosolic glycoproteins, in the range 45-66 kDa, showed a 50-70% decrease of their sialic acid content upon Neu2 expression, supporting their possible role as modulators of the Bcr-Abl complex. N-Acetylneuraminic Acid ABL proto-oncogene 1, non-receptor tyrosine kinase Homo sapiens