Pub. Date : 2007 Mar
PMID : 17332528
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Glucose regulates AMP-activated protein kinase activity and gene expression in clonal, hypothalamic neurons expressing proopiomelanocortin: additive effects of leptin or insulin. | Glucose | proopiomelanocortin | Homo sapiens |
| 2 | The N-43/5 POMC neurons may therefore be an appropriate cell model to study glucose-sensing mechanisms in the hypothalamus. | Glucose | proopiomelanocortin | Homo sapiens |
| 3 | In N-43/5 POMC neurons, increasing glucose concentrations decreased phospho-AMPK activity. | Glucose | proopiomelanocortin | Homo sapiens |
| 4 | As a relevant downstream effect, we found that POMC transcription increased with 2.8 and 16.7 mM glucose. | Glucose | proopiomelanocortin | Homo sapiens |