Title : Structure-based mutation analysis shows the importance of LRP5 beta-propeller 1 in modulating Dkk1-mediated inhibition of Wnt signaling.

Pub. Date : 2007 Apr 15

PMID : 17276019






1 Functional Relationships(s)
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1 Here we show that substitutions of glycine at 171 to K, F, I and Q also resulted in HBM-like activity in the presence of Wnt1 and Dkk1. Glycine dickkopf WNT signaling pathway inhibitor 1 Homo sapiens