Title : Anti-proliferative activity of fenretinide in human hepatoma cells in vitro and in vivo.

Pub. Date : 2007 Jan

PMID : 17159502






1 Functional Relationships(s)
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1 Western blot analysis further showed down-regulation of procaspase-3, X-linked inhibitor of apoptosis protein and poly(ADP-ribose) polymerase cleavage in Bel-7402 cells treated with 15 mumol/l fenretinide for 48 h. Overexpression of p53 was observed in a time-dependent manner, along with a decrease in the Bcl-2/Bax ratio. Fenretinide BCL2 apoptosis regulator Homo sapiens