Title : The effects of modulation of gamma-glutamyl transpeptidase activity in HepG2 cells on thiol homeostasis and caspase-3-activity.

Pub. Date : 2007 Feb

PMID : 17141888






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The results of our studies indicate that the modulation of gammaGT activity can be used to change cellular redox status, and can affect Cys- and Cys-Gly-dependent S-thiolation and caspase-3 activity. Cysteine caspase 3 Homo sapiens
2 The results of our studies indicate that the modulation of gammaGT activity can be used to change cellular redox status, and can affect Cys- and Cys-Gly-dependent S-thiolation and caspase-3 activity. Cysteine caspase 3 Homo sapiens
3 We suggest that the role of high gammaGT activity in HepG2 cells can be connected with production of reactive oxygen species and with S-thiolation with Cys and Cys-Gly that can influence activity of caspase 3. Cysteine caspase 3 Homo sapiens