Title : Protein kinase C-induced activation of a ceramide/protein phosphatase 1 pathway leading to dephosphorylation of p38 MAPK.

Pub. Date : 2006 Dec 1

PMID : 17030510






1 Functional Relationships(s)
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1 Taken together, these data suggest that accumulation of C(16)-ceramide in mitochondria formed from the protein kinase C-dependent salvage pathway results at least in part from the action of longevity-assurance homologue 5, and the generated ceramide modulates the p38 cascade via PP1. N-palmitoylsphingosine inorganic pyrophosphatase 1 Homo sapiens