Title : Rapid broad-spectrum analgesia through activation of peroxisome proliferator-activated receptor-alpha.

Pub. Date : 2006 Dec

PMID : 16997973






2 Functional Relationships(s)
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1 In addition to modulating nociception, GW7647 and PEA reduced hyperalgesic responses in the chronic constriction injury model of neuropathic pain; these effects were also contingent on PPAR-alpha expression and were observed following either acute or subchronic PPAR-alpha agonist administration. GW 7647 peroxisome proliferator activated receptor alpha Mus musculus
2 In addition to modulating nociception, GW7647 and PEA reduced hyperalgesic responses in the chronic constriction injury model of neuropathic pain; these effects were also contingent on PPAR-alpha expression and were observed following either acute or subchronic PPAR-alpha agonist administration. GW 7647 peroxisome proliferator activated receptor alpha Mus musculus