Title : Influence of ciglitazone on A549 cells growth in vitro and in vivo and mechanism.

Pub. Date : 2006

PMID : 16711003






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 There were more cells arrested in G1 /G0 phase and the expression of PPARgamma was markedly up-regulated in ciglitazone-treated group. ciglitazone peroxisome proliferator activated receptor gamma Mus musculus
2 It was concluded that ciglitazone could inhibit A549 proliferation dose-dependently and time-dependently and induce differentiation, which might be related to the modulation of cell cycle interfered by PPARgamma. ciglitazone peroxisome proliferator activated receptor gamma Mus musculus