Title : Inverse but not full benzodiazepine agonists modulate recombinant alpha 6 beta 2 gamma 2 GABAA receptors in transfected human embryonic kidney cells.

Pub. Date : 1991 Sep 16

PMID : 1665550






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Here we report that the imidazobenzodiazepine Ro15-4513 (ethyl 8-azido-5,6-dihydro-5-methyl-6-oxo-4H-imidazo-(1,5-a) (1,4)benzodiazepine-3-carboxylate) reduced GABA-activated currents in recombinant alpha 6 beta 2 gamma 2 and alpha 1 beta 2 gamma 2 receptors, thus acting consistently as an inverse agonist. Ro 15-4513 adrenoceptor alpha 1D Homo sapiens