Title : Regulation of steroid hydroxylase CYP7B1 by androgens and estrogens in prostate cancer LNCaP cells.

Pub. Date : 2006 Jun 2

PMID : 16630558






4 Functional Relationships(s)
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1 The current study showed strong suppression of a human CYP7B1 luciferase reporter gene by dihydrotestosterone (DHT) in prostate cancer LNCaP cells. Dihydrotestosterone cytochrome P450 family 7 subfamily B member 1 Homo sapiens
2 The current study showed strong suppression of a human CYP7B1 luciferase reporter gene by dihydrotestosterone (DHT) in prostate cancer LNCaP cells. Dihydrotestosterone cytochrome P450 family 7 subfamily B member 1 Homo sapiens
3 Also, DHT and overexpression of androgen receptor (AR) suppressed CYP7B1 promoter activity and CYP7B1-mediated catalysis in kidney-derived HEK293 cells. Dihydrotestosterone cytochrome P450 family 7 subfamily B member 1 Homo sapiens
4 Also, DHT and overexpression of androgen receptor (AR) suppressed CYP7B1 promoter activity and CYP7B1-mediated catalysis in kidney-derived HEK293 cells. Dihydrotestosterone cytochrome P450 family 7 subfamily B member 1 Homo sapiens