Title : UVB-induced 1,25(OH)2D3 production and vitamin D activity in intestinal CaCo-2 cells and in THP-1 macrophages pretreated with a sterol Delta7-reductase inhibitor.

Pub. Date : 2006 Sep 1

PMID : 16598763






1 Functional Relationships(s)
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Protein Name
Organism
1 THP-1 macrophages and preconfluent CaCo-2 cells contain the vitamin D receptor (VDR), possess 25-hydroxylase (CYP2R1 and CYP27A1) and 1alpha-hydroxylase (CYP27B1) activity, and survive the low UVB doses essential for vitamin D3 photoproduction. Cholecalciferol GLI family zinc finger 2 Homo sapiens