Title : A dose-response study of graded reoxygenation on the carotid haemodynamics, matrix metalloproteinase-2 activities and amino acid concentrations in the brain of asphyxiated newborn piglets.

Pub. Date : 2006 May

PMID : 16500017






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 There was an oxygen-dependent increase in global cerebral activity of matrix metalloproteinase-2 with specific increases in the basal ganglia of all hypoxic-reoxygenated brains. Oxygen matrix metallopeptidase 2 Homo sapiens
2 CONCLUSIONS: Although using high oxygen concentration to resuscitate asphyxiated newborn piglets increased carotid vascular resistance and cerebral matrix metalloproteinase-2 activity, there is no detrimental effect observed in this acute model of hypoxia-reoxygenation. Oxygen matrix metallopeptidase 2 Homo sapiens