Title : PPARdelta regulates glucose metabolism and insulin sensitivity.

Pub. Date : 2006 Feb 28

PMID : 16492734






3 Functional Relationships(s)
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1 PPARdelta regulates glucose metabolism and insulin sensitivity. Glucose peroxisome proliferator activator receptor delta Mus musculus
2 Euglycemic-hyperinsulinemic-clamp experiments further demonstrate that a PPARdelta-specific agonist suppresses hepatic glucose output, increases glucose disposal, and inhibits free fatty acid release from adipocytes. Glucose peroxisome proliferator activator receptor delta Mus musculus
3 Unexpectedly, gene array and functional analyses suggest that PPARdelta ameliorates hyperglycemia by increasing glucose flux through the pentose phosphate pathway and enhancing fatty acid synthesis. Glucose peroxisome proliferator activator receptor delta Mus musculus