Title : Oxysterol 22(R)-hydroxycholesterol induces the expression of the bile salt export pump through nuclear receptor farsenoid X receptor but not liver X receptor.

Pub. Date : 2006 Apr

PMID : 16371446






2 Functional Relationships(s)
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Protein Name
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1 In contrast to our hypothesis, the oxysterol-induced up-regulation of BSEP is mediated through FXR but not LXR. Oxysterols nuclear receptor subfamily 1 group H member 4 Homo sapiens
2 Mutation of the FXR element IR1 in the BSEP promoter significantly reduced its ability to respond to oxysterol induction. Oxysterols nuclear receptor subfamily 1 group H member 4 Homo sapiens